Abstract Library

#1722 New MEN-1 Gene Mutation Implicated in Familiar MEN-1 Syndrome Onset

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare genetic syndrome associated with an increased risk of developing parathyroid, pituitary and pancreatic neuroendocrine tumors. MEN1 has an autosomal dominant pattern of hereditability and it is usually related to mutations in menin coding gene

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Grego E, Pellicciari M, Novak L, Ortolani S, Antista M,

Keywords: MEN1 syndrome, MEN1 gene mutation, neuroendocrine tumor,

#1380 Assessment of the Growth Rate of Paragangliomas Related to SDHx Gene Mutations Using Computed Tomography.

Introduction: SDHx mutations are associated with a lifelong risk of multifocal paragangliomas (PGL), so patients need regular follow-up examinations.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Ćwikła J

Authors: Michałowska I, Peczkowska M, Cwikła J, Michalski W, Wyrwicz L,

Keywords: SDHx mutation, paraganglioma ,

#1315 Genes Involved in Angiogenesis and mTOR Are Frequently Found Mutated in Asian Patients with Pancreatic Neuroendocrine Tumors.

Introduction: There are limited data and inconsistent findings of genetic alteration in pancreatic neuroendocrine tumors (pNET).

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Wen-Chi C, Yi-Chen Y, Yi-Ming S, Yee C, Po-Han L,

Keywords: pancreatic NETs, gene mutation, mTOR,

#946 Immunohistochemical Staining of Catecholamine-Synthesizing Enzymes in Head and Neck Paraganglioma Tissue

Introduction: Head and neck paragangliomas (HNPGLs) are non-producing neuroendocrine tumors, alhough 19-28% of patients have an increased dopamine production. The high sensitivity of 18F-DOPA PET also shows that these tumors might be able to synthesize catecholamines.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Van der Horst-Schrivers A, Osinga T, Korpershoek E, De Krijger R, Kerstens M,

Keywords: paraganglioma, dopamine,

#942 Ileal Neuroendocrine Well-Differentiated Tumors: Prognostic factors with Focus on Loss of Succinate Dehydrogenase (SDHB) Expression

Introduction: Ileal Neuroendocrine Well-Differentiated Tumors (INWDT) are the most common neuroendocrine neoplasms in the gastrointestinal tract. Gene mutations of SDH complex drive pathogenesis of cancer cells through their role in angiogenesis and cell proliferation.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: MILIONE M

Authors: Milione M, Gasparini P, Pusceddu S, Coppa J, Pellegrinelli A,

Keywords: ileum, neuroendocrine, SDHB, Ki-67, mitosis,